This text introduces students of human geography to the fundamental concept of place, marrying everyday uses of the term with the complex theoretical debates that have grown up around it. A short introduction to one of the most fundamental concepts in human geographyMarries everyday uses of the term "place" with the more complex theoretical debates that have grown up around itMakes the debates intelligible to students, using familiar stories as a way into more abstract ideasExcerpts and discusses key papers on place by Doreen Massey and David HarveyConsiders empirical examples of ways in which the concept of place has been used in researchTeaching and learning aids include an annotated bibliography, lists of key readings and texts, a survey of web resources, suggested pedagogical resources and possible student projects
A new edition of the popular introductory text on the phonological structure of present-day English. A clear and accessible introductory text on the phonological structure of the English language, English Phonetics and Phonology is an ideal text for those with no prior knowledge of the subject. This market-leading textbook teaches undergraduate students and non-native English speakers the fundamentals of articulatory phonetics and phonology in an engaging, easy-to-understand style. Rigorously expanded to include new materials on first and second language acquisition of English phonetics and phonology, this third edition, English Phonetics and Phonology boasts two new chapters on first-language and second-language acquisition of English phonetics and phonology. By introducing topics such as the mental lexicon and the emergence of phonological rules and representations, and graphophonemic problems in L2 acquisition, these two new chapters have been added to afford greater flexibility for teachers and increased support for non-native English speakers. Expanded website content includes exercise-linked sound files. Based on the author's 34 years of teaching English Phonetics and Phonology in the UK and France Includes coverage of various accents in English and second-language acquisition Hugely successful textbook for the introductory Phonetics course, now in its third edition References and exercises across all chapters to guide students throughout the work Provides access to companion website for additional learning tools, sound files, and instructor resources English Phonetics and Phonology is an indispensable resource for undergraduate students in courses on Phonetics and Phonology with no prior knowledge of theoretical linguistics and non-native English speakers alike.
This tenth anniversary revised edition of the authoritative text on Christianitys first thousand years of history features a new preface, additional color images, and an updated bibliography. The essential general survey of medieval European Christendom, Browns vivid prose charts the compelling and tumultuous rise of an institution that came to wield enormous religious and secular power.Clear and vivid history of Christianitys rise and its pivotal role in the making of Europe Written by the celebrated Princeton scholar who originated of the field of study known as late antiquity Includes a fully updated bibliography and index
This book provides a clear and comprehensive introduction to Tibet, its culture and history.A clear and comprehensive overview of Tibet, its culture and history.Responds to current interest in Tibet due to continuing publicity about Chinese rule and growing interest in Tibetan Buddhism.Explains recent events within the context of Tibetan history.Situates Tibet in relation to other Asian civilizations through the ages.Draws on the most recent scholarly and archaeological research.Introduces Tibetan culture particularly social institutions, religious and political traditions, the arts and medical lore.An epilogue considers the fragile position of Tibetan civilization in the modern world.
This concise and lively survey introduces students with no prior knowledge to Chaucer, and particularly to The Canterbury Tales. Provides essential facts about Chaucer, as well as a framework for thinking about his poetry. Encourages an engaged reading of The Canterbury Tales. Introduces students to the historical and religious background needed to understand the contexts in which Chaucer wrote.
Provides essential facts about Chaucer, as well as a framework for thinking about his poetry.
Encourages an engaged reading of The Canterbury Tales.
Introduces students to the historical and religious background needed to understand the contexts in which Chaucer wrote.
This book presents the issues surrounding the conservation of wild species and ecosystems used by people. It is aimed at final year undergraduate and master's students taking courses in conservation, environmental management, ecological economics and related subjects, as well as conservation professionals, including managers, policy-makers and researchers. The structure of the book is ideal for a course in conservation, comprising a theoretical section written by the authors, and a set of ten contributed case studies intentionally diverse in discipline, geographical region and system of study. The theoretical section provides the knowledge that is needed to understand the issues, while the case studies can form the basis of seminars. Readers will emerge with a clear recognition of the difficulties of limiting the harvesting of biological resources to sustainable levels, and of the boundaries of sustainable use as a conservation tool.
The authors, an ecologist and an anthropologist, have both worked on the conservation and sustainable use of wildlife for several years, including the ivory and rhino horn trades. The first book to examine the issues underlying the sustainable use debate in a fully interdisciplinary manner. Both the theoretical section and the case studies approach the issues using methods from economics, ecology, anthropology and other fields Designed as a course textbook, combining a theoretical section with invited case studies written by expert practitioners in the field Outlines the new direction that conservation biology (and thus conservation biologists) must take if it is to be successful
The deep sea covers over 60% of the surface of the earth, yet less than 1% has been scientifically investigated. There is growing pressure on deep-sea resources and on researchers to deliver information on biodiversity and the effects of human impacts on deep-sea ecosystems. Although scientific knowledge has increased rapidly in recent decades, there exist large gaps in global sampling coverage of the deep sea, and major efforts continue to be directed into offshore research. Biological Sampling in the Deep Sea represents the first comprehensive compilation of deep-sea sampling methodologies for a range of habitats. It reviews the real life applications of current, and in some instances developing, deep-sea sampling tools and techniques. In creating this book the authors have been able to draw upon the experiences of those at the ?coal face? of deep-sea sampling, expanding on the existing methodological texts whilst encompassing a level of technical detail often omitted from journal publications. Ultimately the book will promote international consistency in sampling approaches and data collection, advance the integration of information into global databases, and facilitate improved data analyses and consequently uptake of science results for the management and conservation of the deep-sea environment. The book will appeal to a range of readers, including students, early-career through to seasoned researchers, as well as environmental managers and policy makers wishing to understand how the deep-sea is sampled, the challenges associated with deep survey work, and the type of information that can be obtained.
As in previous editions of this popular text on cross-cultural management, students will find here an invaluable guide to key management theories, linked to practical examples from all round the world. The book's key distinctive feature remains its truly international profile, with current examples from the US, Europe, Asia and new perspectives in this edition from other regions.
Discussion of cross-cultural models is updated by including the 'crossvergence' framework developed during the 1990s, as well as the latest new research on organizational culture
Coverage of how and to what extent cultural variation affects the implementation of e-technology at the workplace (esp. in multinational subsidiaries)
New material on the management of marketing/sales teams across borders and implications of cultural differences for expatriate managers.
The addition of several new cases, from the Middle East, Latin America and Africa as well as new cases in in Asia.
The 4th edition retains the special appendix on how to write a successful dissertaion or project which makes this a useful text for both MBA and advanced undergraduate courses.
The magnitude of the food-waste disposal problem cannot be understated. Utilisation of food waste is of concern to the food processing industry, consumers, environmentalists, and regulators of handling and disposal systems. Food waste is not consistent in quality, is usually high in moisture content, and is only available locally. This book focuses on the challenges of utilising both wet and/or processed food waste. The regulatory environment relating to food waste, the perspective of the end-users, and practical use as animal feed is also discussed. One of the goals of this publication, other than to give a clear explanation of the subject of food waste and its uses as animal feed, is to stimulate a need for research.
Minerals and rocks form the foundation of geologic studies. This new textbook has been written to address the needs of students at the increasing number of universities that have compressed separate mineralogy and petrology courses into a one- or two-semester Earth materials course.
Key features of this book include:equal coverage of mineralogy, sedimentary petrology, igneous petrology and metamorphic petrology;copious field examples and regional relationships with graphics that illustrate the concepts discussed;numerous case studies to show the uses of earth materials as resources and their fundamental role in our lives and the global economy, and their relation to natural and human-induced hazards;the integration of earth materials into a cohesive process-based earth systems framework;two color thoughout with 48 pages of four color.Readership: students taking an earth materials, or combined mineralogy and petrology course in an earth science degree program. It will also be useful for environmental scientists, engineering geologists, and physical geographers who need to learn about minerals, rocks, soil and water in a comprehensive framework.A companion website for this book is available at: www.wiley.com/go/hefferan/earthmaterials.
Provides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day. Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell differentiation, autophagy, and apoptosis. The text goes on to explore how these processes are disturbed in the various diseases of the bone marrow, blood, and lymphoid systems. Helps solve difficult diagnostic challenges and covers complex principles using highly illustrative, full-color images Explores all aspects of benign and malignant hematology, including blood transfusion and coagulation with extensive coverage of the pathogenesis of common clinical entities Provides a quick and easy reference of key diagnostic issues in a comprehensive yet concise format Includes and illustrates the WHO Classification of Hematologic Malignancies Illustrates the new knowledge of the molecular basis of inherited and acquired blood diseases Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease is the must-have resource for both trainee and practising hematologists, and for every department of hematology.
"Substantially updated and now multi-authored so that all aspects of haematology are equally covered, including the newest developments in molecular biology and genomic sequencing"
"There is a surplus of invention in communicating complex problems here and an admirable effort to keep the reader totally up-to-date"
The Union for International Cancer Control's (UICC) TNM classification system is the most widely used cancer classification and staging system in the world. It is used to describe the anatomical extent of disease and it is essential to patient care, research and cancer control. This fifth edition of the TNM Supplement: A Commentary of Uniform Use offers practitioners a wealth of material intended to complement the system's day-to-day use. The volume features: Updated definitions of terms used in cancer staging. New sections on carcinomas of the thymus, sarcomas of the spine and pelvis and soft tissue sarcomas of the head and neck, and comprehensive updates to the head and neck carcinomas, carcinomas of the lung and neuroendocrine tumours sections. Frequently asked questions from the UICC helpdesk. The Supplement may be treated as a companion text to the recent eighth edition of the TNM Classification of Malignant Tumours (978-1-119-26357-9), supporting the correct and uniform application of the TNM classification system. The TNM Supplement can also be utilised as a standalone book, providing explanations and examples to answer many questions that arise during the daily use of the TNM cancer classification and staging system, particularly in unusual cases.
Structured like a textbook, the second edition of this reference covers all aspects of biopharmaceutical manufacturing, including legal and regulatory issues, production facility design, and quality assurance, with a focus on supply chain management and regulations in emerging markets and cost control.
The author has longstanding industrial expertise in biopharmaceutical production and years of experience teaching at universities. As such, this practical book is ideal for use in academia as well as for internal training within companies.
Das Buch ist eine systematische Einführung in die Praxis guter Wissenschaftskommunikation. Anhand zahlreicher Beispiele erklärt es, wie Wissenschaftler, Öffentlichkeitsarbeiter und Journalisten unterschiedliche Zielgruppen über Forschung informieren knnen und dabei die wichtigsten medialen Formate nutzen: Meldungen, Artikel, Kommentare, Vorträge, Interviews, soziale Netzwerke, Weblogs usw.
Aus dem Inhalt:
- Allgemeine Regeln für gutes Formulieren
- Praxis guter Wissenschaftskommunikation: Überschrift, Vorspann, Bildunterschrift, Metaphern usw.
- Spezielle mediale Formen: Meldungen, Kommentare, Rezensionen, Vorträge, Interviews usw.
- Wissenschaftskommunikation per Internet: Blogs, soziale Netzwerke, die persnliche Webseite
- Ausblick: 10 Thesen zur Zukunft der Wissenschaftskommunikation
Written by an international team of experts from the Tara Oceans Marine Biology Imaging Platform (TAOMI), this is the first and only compendium on marine imaging technologies, and includes all known underwater as well as on-land techniques.
TAOMI is imaging the largest collection of marine organisms in recent history, ranging from viruses to corals, and is duplicated on land to perform high throughput confocal analysis of plankton, X-ray tomography as well as cryo-electron microscopy. This unique platform combines underwater imaging with cytometry, stereomicroscopy, fluorescence microscopy and 3D microscopy - all of which are covered in this practical book, along with remote sensing, MRI, and optical projection tomography.
The definitive resource for every marine biologist who is planning to image marine species, whether underwater or on land.
Now in its fourth edition, this textbook is one of the few titles worldwide to cover enzyme kinetics in its entire scope and the only one to include its implications for bioinformatics and systems biology. Multi-enzyme complexes and cooperativity are therefore treated in more detail than in any other textbook on the market.
The respected and well known author is one of the most experienced researchers into the topic and writes with outstanding style and didactic clarity. As with the previous editions, he presents here steady-state kinetics and fast reactions, supplementing each chapter with problems and solutions. For the first time, this edition features a companion website providing all figures in colour
A thorough introduction to the basics of bioengineering, with a focus on applications in the emerging "white" biotechnology industry.
As such, this latest volume in the "Advanced Biotechnology" series covers the principles for the design and analysis of industrial bioprocesses as well as the design of bioremediation systems, and several biomedical applications. No fewer than seven chapters introduce stoichiometry, kinetics, thermodynamics and the design of ideal and real bioreactors, illustrated by more than 50 practical examples. Further chapters deal with the tools that enable an understanding of the behavior of cell cultures and enzymatically catalyzed reactions, while others discuss the analysis of cultures at the level of the cell, as well as structural frameworks for the successful scale-up of bioreactions. In addition, a short survey of downstream processing options and the control of bioreactions is given.
With contributions from leading experts in industry and academia, this is a comprehensive source of information peer-reviewed by experts in the field.
Molecular biotechnology continues to triumph, as this textbook testifies - edited by one of the academic pioneers in the field and written by experienced professionals. This completely revised second edition covers the entire spectrum, from the fundamentals of molecular and cell biology, via an overview of standard methods and technologies, the application of the various "-omics", and the development of novel drug targets, right up to the significance of system biology in biotechnology. The whole is rounded off by an introduction to industrial biotechnology as well as chapters on company foundation, patent law and marketing.
The new edition features:
- Large format and full color throughout
- Proven structure according to basics, methods, main topics and economic perspectives
- New sections on system biology, RNA interference, microscopic techniques, high throughput sequencing, laser applications, biocatalysis, current biomedical applications and drug approval
- Optimized teaching with learning targets, a glossary containing around 800 entries, over 500 important abbreviations and further reading.
The only resource for those who are seriously interested in the topic.
Bonus material available online free of charge: www.wiley-vch.de/home/molecbiotech
A well-balanced overview of mathematical approaches to complex systems ranging from applications in chemistry and ecology to basic research questions on network complexity. Matthias Dehmer, Abbe Mowshowitz, and Frank
Emmert-Streib, well-known pioneers in the fi eld, have edited this volume with a view to balancing classical and modern approaches to ensure broad coverage of contemporary research problems.
The book is a valuable addition to the literature and a must-have for anyone dealing with network compleaity and complexity issues.
Still the most comprehensive reference source on the development, production and therapeutic application of antibodies, this second edition is thoroughly updated and now has 30% more content.
Volume 1 covers selection and engineering strategies for new antibodies, while the second volume presents novel therapeutic concepts and antibodies in clinical study, as well as their potential. Volumes 3 and 4 feature detailed and specific information about each antibody approved for therapeutic purposes, including clinical data. This unique handbook concludes with a compendium of marketed monoclonal antibodies and an extensive index.
Beyond providing current knowledge, the authors discuss emerging technologies, future developments, and intellectual property issues, such that this handbook meets the needs of academic researchers, decision makers in industry and healthcare professionals in the clinic.
The second edition of this successful textbook, completely revised and largely expanded. In particular the section on the analysis of genome data is covered in much greater depth and chapters added on machine learning, Bayesian networks, protein and enzyme designs as well as the evaluation of microarrays. Furthermore an attractive website with supplementary material and problems is available: WWW.WILEY-VCH.DE/HOME/BIOINFORMATIK
Der "kleine" Alberts gilt als das beliebteste einführende Lehrbuch der Zellbiologie: wie die vierte, komplett überarbeitete Auflage zeigt, auch vllig zu Recht. Wieder ist besonders viel Wert auf eine anschauliche Präsentation in Text und Bild gelegt worden. Ein ausgefeiltes didaktisches Konzept vereinigt Bewährtes mit vllig Neuem:
- inklusive CD-ROM "Essential Cell Biology Interactive" mit über 100 Video Clips, Molekülstrukturen und mikroskopischen Aufnahmen
- 20 Tafeln zu klassischen und modernen Experimenten der Biologie
- mit zwei neuen Kapiteln zu "Genetik, Meiose und die molekularen Grundlagen der Vererbung" sowie "Wie sich Gene und Genome entwickeln"
- Zusammenfassung der wichtigsten Inhalte und Schlüsselbegriffe am Kapitelende
- durchgehend vierfarbige Illustrationen und Übersichtstafeln, die die grundlegenden Konzepte anschaulich darstellen
- mit über 400 Verständnisfragen, Übungsaufgaben und deren Lsungen
- um mehr als 10 % erweitertes, illustriertes Glossar mit 600 Ausdrücken
Aus der Fülle der neuen und neuesten Erkenntnisse wurden die unentbehrlichen Grundlagen der molekularen Zellbiologie sowie ihre Anwendungen in Medizin, Gen- und Biotechnologie herausgearbeitet - ein Plus, das dieses Buch, zusammen mit seinem unverwechselbaren Stil, für Lehrende und Lernende gleichermaßen faszinierend und verlässlich macht.
Seit dem Erscheinen der ersten Auflage 1994 ist das Lehrbuch "Hämatologie" nicht mehr zu stoppen. Die vorliegende neue, stark überarbeitete und aktualisierte Auflage integriert den neuesten Stand der MTA-Ausbildung. Das Buch orientiert sich thematisch am Lehrinhaltskatalog des Deutschen Verbands Technischer Assistentinnen und Assistenten in der Medizin (dvta). Didaktisch ausgeklügelt ist der Band eine unerlässliche Hilfe in der Ausbildung.
Drei Jahre dauert die Ausbildung zur/zum MTA. Es sind drei lernintensive Jahre mit einem anspruchsvollen Mix aus Theorie und Praxis. "Hämatologie" ist das bewährte Lehrbuch, das nun schon einige Generationen von MTA-Auszubildenden begleitet hat.
Das Buch gliedert sich in einen theoretischen und einen praktischen Teil. Ersterer behandelt die Grundlagen der Hämatologie und ihrer Krankheitsbilder. Der praktische Teil vermittelt die in der hämatologischen Diagnostik und Therapie verwendeten Techniken. Es gibt zahlreiche Handlungsanleitungen für die tägliche Arbeit. Daneben wird kompetent in Physiologie, Pathophysiologie und Labordiagnostik eingeführt.
Der übersichtliche Aufbau sowie etliche erläuternde Tabellen und Abbildungen erleichtern das Verständnis. Und die überzeugende Stoffvermittlung macht vor allem eines deutlich: Die Autoren bringen jahrelange Erfahrung aus der MTA-Ausbildung mit.
Dabei trägt die neue Auflage den umfangreichen Fortschritten Rechnung, die insbesondere in der molekularbiologischen Diagnostik erreicht wurden.
Um ein biologisches Experiment richtig planen, durchf hren und auswerten zu k nnen, muss man ber fundierte Kenntnisse grundlegender mathematischer und statistischer Operationen verf gen. Mathe f r Biologen bietet einen leicht verst ndlichen Zugang zur Mathematik, Statistik und Datenverarbeitung. Ob in Form von Exponentialrechnungen, Logarithmen oder bei der Berechnung von Molarit ten, Verd nnungen und Volumina - ohne Mathematik geht im Labor gar nichts. Die Kenntnis aller relevanten Ma einheiten und Umrechnungsverh ltnisse ist ebenso unverzichtbar wie eine sichere Beherrschung der wichtigsten statistischen Methoden und der Prinzipien der Wahrscheinlichkeitsrechnung. All dies vermittelt Mathe f r Biologen. Besonders junge Wissenschaftler, Diplomanden, Doktoranden und Angeh rige des technischen Personals d rften die einf hlsame Didaktik, den klaren Aufbau und die verst ndliche Sprache des Bandes zu sch tzen wissen. Jedes der elf Kapitel enth lt Kontrollfragen, anhand derer der Leser seine Lernfortschritte berpr fen kann. Die L sungen werden im Anhang ausf hrlich hergeleitet und erl utert. Das umfangreiche Glossar erschlie t die wichtigsten Fachbegriffe. So empfiehlt sich der Band sowohl als Begleiter bei der t glichen Laborarbeit als auch zum Nachschlagen beim Verfassen wissenschaftlicher Arbeiten.